Extraordinary Measures is a 2010 drama film starring Brendan Fraser, Harrison Ford, and Keri Russell. It is distributed by CBS Films and was released on January 22, 2010. It is about parents who form a biotechnology company to develop a drug to save the lives of their children, who have a life-threatening disease. The film is based on the true story of John and Aileen Crowley, whose children had Pompe's disease. The film was shot in St. Paul, Oregon, Portland and Beaverton, Oregon as well as Vancouver, Washington. It is the first film to go into production for CBS Films, the film division of CBS Corporation.
Brendan Fraser plays John Crowley, a biotechnology executive whose two youngest children were afflicted with Pompe disease or acid maltase deficiency. Along with his wife Aileen (Keri Russell), he raises money for research scientist Robert Stonehill (Harrison Ford), forming a company to develop a drug to save his children's lives. Dr. Stonehill is based on real life doctor Yuan-Tsong Chen.
The film centers on the Crowleys' two dying children, aged 9 and 7. In real life, most children with Pompe disease would die before age 2. There is also a juvenile and adult form which can present at almost any age. Those in the real story were 15 months and 7 days old when they got sick. They were 5 and 4 years old when treatment began.
Adapted by Robert Nelson Jacobs from a nonfiction book by the journalist Geeta Anand, the film is also an examination of how medical research is conducted and financed.